Towards the end of the last century, at the Universidad Central de Las Villas, the investigations in blended cements began to concentrate on the use of clays. In 2004, Prof Karen Scrivener from EPFL in Switzerland and Prof Fernando Martirena from UCLV discussed for the first time about the use of calcined clays for pozzolans. In 2005, Scrivener and Martirena launched together the first research project on this topic supported by the Swiss National Science Foundation (SNSF) and the Swiss Agency of Development and Cooperation (SDC). 

In 2013, a global project on Limestone Calcined Clay Cement was formed, integrating India as second focus region. Since 2017 two Technology Research Centers in Cuba and India were set up. In the course of this phase academic, and policy circles as well as the top global cement producers widely acknowledged LC³ as the technology with the highest potential to lower CO₂-emissions in the cement sector. The investigation of economic feasibility and the possibility of color control were milestones for the industrial engagement. The technology has received high attention for example by Bloomberg and TED-talks.

The TRC LATAM maintains an active role in the research of new applications for LC³ with more than 8 PhD projects and the participation in the most significant worldwide scientific events. Its members are also involved in INNOVANDI’s project “Calcined Clays” focusing on knowledge exchange between academia and the industry. During the 2021 TRC Latin America has developed a new formula for dry mortar based on LC³ with high expansive properties, especially designed for its application in sealing joints in water channels in Cuba. Other similar products are also in development process.